Water is essential for drinking, sanitation, and food production; for billions of people, however, water access and quality are limited. The COVID-19 pandemic has further amplified the impacts of these water inequalities. Claudia Sadoff and Mark Smith of the International Water Management Institute assess the role of water in the current responses to COVID-19 and in future phases of recovery and resilience. Their recommendations range from emergency provision of water to high-risk groups, through developing new innovations for water supply and reuse, to scaling strategies for smarter allocation of water to multiple essential uses.—John McDermott, series co-editor and Director, CGIAR Research Program on Agriculture for Nutrition and Health (A4NH).